| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DYM (1-250) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DYM |
| Gene ID: |
54808 |
| Uniprot ID: |
DYM_HUMAN |
| Immunogen Region: |
1-250 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DYM (NP_060123.3). |
| Immunogen Sequence: |
MGSNSSRIGDLPKNEYLKKL SGTESISENDPFWNQLLSFS FPAPTSSSELKLLEEATISV CRSLVENNPRTGNLGALIKV FLSRTKELKLSAECQNHIFI WQTHNALFIICCLLKVFICQ MSEEELQLHFTYEEKSPGNY SSDSEDLLEELLCCLMQLIT DIPLLDITYEISVEAISTMV VFLSCQLFHKEVLRQSISHK YLMRGPCLPYTSKLVKTLLY NFIRQEKPPPPGAHVFPQQ |
| Tissue Specificity | Expressed in most embryo-fetal and adult tissues. Abundant in primary chondrocytes, osteoblasts, cerebellum, kidney, lung, stomach, heart, pancreas and fetal brain. Very low or no expression in the spleen, thymus, esophagus, bladder and thyroid gland. |
| Post Translational Modifications | Myristoylated in vitro.myristoylation is not essential for protein targeting to Golgi compartment. |
| Function | Necessary for correct organization of Golgi apparatus. Involved in bone development. |
| Protein Name | DymeclinDyggve-Melchior-Clausen Syndrome Protein |
| Cellular Localisation | CytoplasmGolgi ApparatusMembraneLipid-AnchorSequence Analysis Programs Clearly Predict 1 Transmembrane RegionHoweverPubmed:18996921 Shows That It Is Not A Stably Anchored Transmembrane Protein But It Weakly Associates With The Golgi Apparatus And Shuttles Between The Golgi And The Cytosol |
| Alternative Antibody Names | Anti-Dymeclin antibodyAnti-Dyggve-Melchior-Clausen Syndrome Protein antibodyAnti-DYM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
