| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DSG4 (480-630) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DSG4 |
| Gene ID: |
147409 |
| Uniprot ID: |
DSG4_HUMAN |
| Immunogen Region: |
480-630 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_817123.1). |
| Immunogen Sequence: |
TGTICIEVPDINDYCPNIFP ERRTICIDSPSVLISVNEHS YGSPFTFCVVDEPPGIADMW DVRSTNATSAILTAKQVLSP GFYEIPILVKDSYNRACELA QMVQLYACDCDDNHMCLDSG AAGIYTEDITGDTYGPVTED QAGVSNVGLGP |
| Tissue Specificity | Highly expressed in skin, testis and prostate.less in salivary gland. In scalp follicles, present in the inner root sheath (IRS) and all layers of the matrix and precortex. |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes. |
| Protein Name | Desmoglein-4Cadherin Family Member 13 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative Antibody Names | Anti-Desmoglein-4 antibodyAnti-Cadherin Family Member 13 antibodyAnti-DSG4 antibodyAnti-CDHF13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
