| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CTDSP1 (1-90) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CTDSP1 |
| Gene ID: |
58190 |
| Uniprot ID: |
CTDS1_HUMAN |
| Immunogen Region: |
1-90 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human CTDSP1 (NP_067021.1). |
| Immunogen Sequence: |
MDSSAVITQISKEEARGPLR GKGDQKSAASQKPRSRGILH SLFCCVCRDDGEALPAHSGA PLLVEENGAIPKQTPVQYLL PEAKAQDSDK |
| Tissue Specificity | Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta. |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. |
| Protein Name | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1Nuclear Lim Interactor-Interacting Factor 3Nli-IfNli-Interacting Factor 3Small C-Terminal Domain Phosphatase 1Scp1Small Ctd Phosphatase 1 |
| Cellular Localisation | NucleusColocalizes With Rna Polymerase Ii |
| Alternative Antibody Names | Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 antibodyAnti-Nuclear Lim Interactor-Interacting Factor 3 antibodyAnti-Nli-If antibodyAnti-Nli-Interacting Factor 3 antibodyAnti-Small C-Terminal Domain Phosphatase 1 antibodyAnti-Scp1 antibodyAnti-Small Ctd Phosphatase 1 antibodyAnti-CTDSP1 antibodyAnti-NIF3 antibodyAnti-NLIIF antibodyAnti-SCP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
