• Western blot analysis of extracts of mouse brain, using Caspr2/Caspr2/CNTNAP2 antibody (STJ29602) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-CNTNAP2 antibody (180-400) (STJ29602)

SKU:
STJ29602

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CNTNAP2 (180-400) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTNAP2
Gene ID: 26047
Uniprot ID: CNTP2_HUMAN
Immunogen Region: 180-400
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human Caspr2/Caspr2/CNTNAP2 (NP_054860.1).
Immunogen Sequence: GCSYWADVINFDGHVVLPYR FRNKKMKTLKDVIALNFKTS ESEGVILHGEGQQGDYITLE LKKAKLVLSLNLGSNQLGPI YGHTSVMTGSLLDDHHWHSV VIERQGRSINLTLDRSMQHF RTNGEFDYLDLDYEITFGGI PFSGKPSSSSRKNFKGCMES INYNGVNITDLARRKKLEPS NVGNLSFSCVEPYTVPVFFN ATSYLEVPGRLNQDLFSVSF Q
Tissue Specificity Predominantly expressed in nervous system.
Function Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
Protein Name Contactin-Associated Protein-Like 2
Cell Recognition Molecule Caspr2
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Cell Junction
Paranodal Septate Junction
Expressed In The Juxtaparadonal Region
Alternative Antibody Names Anti-Contactin-Associated Protein-Like 2 antibody
Anti-Cell Recognition Molecule Caspr2 antibody
Anti-CNTNAP2 antibody
Anti-CASPR2 antibody
Anti-KIAA0868 antibody

Information sourced from Uniprot.org

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