| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNOT10 |
| Gene ID: | 25904 |
| Uniprot ID: | CNO10_HUMAN |
| Immunogen Region: | 465-744 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 465-744 of human CNOT10 (NP_056257.1). |
| Immunogen Sequence: | LRNALLLLPEEQQDPKQENG AKNSNQLGGNTESSESSETC SSKSHDGDKFIPAPPSSPLR KQELENLKCSILACSAYVAL ALGDNLMALNHADKLLQQPK LSGSLKFLGHLYAAEALISL DRISDAITHLNPENVTDVSL GISSNEQDQGSDKGENEAME SSGKRAPQCYPSSVNSARTV MLFNLGSAYCLRSEYDKARK CLHQAASMIHPKEVPPEAIL LAVYLELQNGNTQLALQII |
| Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. |
| Protein Name | Ccr4-Not Transcription Complex Subunit 10 |
| Database Links | Reactome: R-HSA-429947Reactome: R-HSA-6804115Reactome: R-HSA-9820841 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ccr4-Not Transcription Complex Subunit 10 antibodyAnti-CNOT10 antibody |
Information sourced from Uniprot.org