| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CNOT10 (465-744) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNOT10 |
| Gene ID: |
25904 |
| Uniprot ID: |
CNO10_HUMAN |
| Immunogen Region: |
465-744 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 465-744 of human CNOT10 (NP_056257.1). |
| Immunogen Sequence: |
LRNALLLLPEEQQDPKQENG AKNSNQLGGNTESSESSETC SSKSHDGDKFIPAPPSSPLR KQELENLKCSILACSAYVAL ALGDNLMALNHADKLLQQPK LSGSLKFLGHLYAAEALISL DRISDAITHLNPENVTDVSL GISSNEQDQGSDKGENEAME SSGKRAPQCYPSSVNSARTV MLFNLGSAYCLRSEYDKARK CLHQAASMIHPKEVPPEAIL LAVYLELQNGNTQLALQII |
| Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. |
| Protein Name | Ccr4-Not Transcription Complex Subunit 10 |
| Database Links | Reactome: R-HSA-429947Reactome: R-HSA-6804115 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ccr4-Not Transcription Complex Subunit 10 antibodyAnti-CNOT10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
