Tissue Specificity | Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney. |
Function | Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner. |
Protein Name | Cytoskeleton-Associated Protein 2Ctcl Tumor Antigen Se20-10Tumor- And Microtubule-Associated Protein |
Cellular Localisation | CytoplasmCytoskeletonSpindleSpindle PoleContrary To The Ectopically Expressed ProteinEndogenous Ckap2 Does Not Colocalize With Microtubules In G1S And Early G2At Late G2 And Prophase After Separation Of Duplicated CentrosomesColocalizes With Gamma-Tubulin And Centrosome-Proximal MicrotubulesFrom Prometaphase Through Anaphase BColocalizes With Mitotic Spindle Poles And Spindle MicrotubulesDuring CytokinesisAbsent From Midbody Microtubules |
Alternative Antibody Names | Anti-Cytoskeleton-Associated Protein 2 antibodyAnti-Ctcl Tumor Antigen Se20-10 antibodyAnti-Tumor- And Microtubule-Associated Protein antibodyAnti-CKAP2 antibodyAnti-LB1 antibodyAnti-TMAP antibody |
Information sourced from Uniprot.org