| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CKAP2 |
| Gene ID: | 26586 |
| Uniprot ID: | CKAP2_HUMAN |
| Immunogen Region: | 335-460 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 335-460 of human CKAP2 (NP_001273616.1). |
| Immunogen Sequence: | EKSEPVDQRRHTAGKAIVDS RSAQPKETSEERKARLSEWK AGKGRVLKRPPNSVVTQHEP AGQNEKPVGSFWTTMAEEDE QRLFTEKVNNTFSECLNLIN EGCPKEDILVTLNDLIKNIP DAKKLV |
| Tissue Specificity | Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney. |
| Function | Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner. |
| Protein Name | Cytoskeleton-Associated Protein 2 Ctcl Tumor Antigen Se20-10 Tumor- And Microtubule-Associated Protein |
| Cellular Localisation | Cytoplasm Cytoskeleton Spindle Spindle Pole Contrary To The Ectopically Expressed Protein Endogenous Ckap2 Does Not Colocalize With Microtubules In G1 S And Early G2 At Late G2 And Prophase After Separation Of Duplicated Centrosomes Colocalizes With Gamma-Tubulin And Centrosome-Proximal Microtubules From Prometaphase Through Anaphase B Colocalizes With Mitotic Spindle Poles And Spindle Microtubules During Cytokinesis Absent From Midbody Microtubules |
| Alternative Antibody Names | Anti-Cytoskeleton-Associated Protein 2 antibody Anti-Ctcl Tumor Antigen Se20-10 antibody Anti-Tumor- And Microtubule-Associated Protein antibody Anti-CKAP2 antibody Anti-LB1 antibody Anti-TMAP antibody |
Information sourced from Uniprot.org