• Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using CHD4 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HepG2 cells, using CHD4 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-CHD4 antibody (571-620 aa) (STJ94119)

SKU:
STJ94119

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Chromodomain-helicase-DNA-binding protein 4 (571-620 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHD4
Gene ID: 1108
Uniprot ID: CHD4_HUMAN
Immunogen Region: 571-620 aa
Specificity: Mi2-Beta Polyclonal Antibody detects endogenous levels of Mi2-Beta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CHD4 at the amino acid range 571-620
Function ATP-dependent helicase that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis.
Protein Name Chromodomain-Helicase-Dna-Binding Protein 4
Chd-4
Atp-Dependent Helicase Chd4
Mi-2 Autoantigen 218 Kda Protein
Mi2-Beta
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-427389
Reactome: R-HSA-6804758
Reactome: R-HSA-73762
Reactome: R-HSA-8943724
Reactome: R-HSA-9031628
Reactome: R-HSA-9679191
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Associates With Centrosomes In Interphase
Localizes To Sites Of Dna Damage In A Manner Dependent On Zmynd8 And Znf687
Alternative Antibody Names Anti-Chromodomain-Helicase-Dna-Binding Protein 4 antibody
Anti-Chd-4 antibody
Anti-Atp-Dependent Helicase Chd4 antibody
Anti-Mi-2 Autoantigen 218 Kda Protein antibody
Anti-Mi2-Beta antibody
Anti-CHD4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance