• Western blot analysis of lysates from Rat liver, using CCL16 Rabbit polyclonal antibody (STJ117512) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CCL16 antibody (1-120) (STJ117512)

SKU:
STJ117512

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Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CCL16 (1-120) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL16
Gene ID: 6360
Uniprot ID: CCL16_HUMAN
Immunogen Region: 1-120
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CCL16 (NP_004581.1).
Immunogen Sequence: MKVSEAALSLLVLILIITSA SRSQPKVPEWVNTPSTCCLK YYEKVLPRRLVVGYRKALNC HLPAIIFVTKRNREVCTNPN DDWVQEYIKDPNLPLLPTRN LSTVKIITAKNGQPQLLNSQ
Tissue Specificity Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Function Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Protein Name C-C Motif Chemokine 16
Chemokine Cc-4
Hcc-4
Chemokine Lec
Il-10-Inducible Chemokine
Lcc-1
Liver-Expressed Chemokine
Lymphocyte And Monocyte Chemoattractant
Lmc
Monotactin-1
Mtn-1
Ncc-4
Small-Inducible Cytokine A16
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 16 antibody
Anti-Chemokine Cc-4 antibody
Anti-Hcc-4 antibody
Anti-Chemokine Lec antibody
Anti-Il-10-Inducible Chemokine antibody
Anti-Lcc-1 antibody
Anti-Liver-Expressed Chemokine antibody
Anti-Lymphocyte And Monocyte Chemoattractant antibody
Anti-Lmc antibody
Anti-Monotactin-1 antibody
Anti-Mtn-1 antibody
Anti-Ncc-4 antibody
Anti-Small-Inducible Cytokine A16 antibody
Anti-CCL16 antibody
Anti-ILINCK antibody
Anti-NCC4 antibody
Anti-SCYA16 antibody

Information sourced from Uniprot.org

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