| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Calcyon (1-50) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.75 µg/µl |
| Dilution Range: | WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Caly |
| Gene ID: | 192349 |
| Uniprot ID: | CALY_RAT |
| Immunogen Region: | 1-50 |
| Immunogen: | Synthetic peptide taken within amino acid region 1-50 on rat Calcyon protein. |
| Tissue Specificity | Expressed exclusively in neurons (at protein level). In all age groups, expressed at significantly higher levels in the medial prefrontal and orbital frontal cortices of spontaneously hypertensive rats (SHR), a model of attention deficit-hyperactivity disorder, than Wistar Kyoto (WKY) animals. In the motor cortex, dorsal striatum and nucleus accumbens, expression is significantly elevated in SHR only in younger animals. |
| Function | Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. |
| Protein Name | Neuron-Specific Vesicular Protein Calcyon |
| Cellular Localisation | Cytoplasmic Vesicle MembraneSingle-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Neuron-Specific Vesicular Protein Calcyon antibodyAnti-Caly antibodyAnti-Drd1ip antibody |
Information sourced from Uniprot.org
