Western blot analysis of lysates from mouse liver, using CADM2 Rabbit polyclonal antibody (STJ113322) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CADM2 antibody (220-335) (STJ113322)

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STJ113322
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CADM2
Gene ID: 253559
Uniprot ID: CADM2_HUMAN
Immunogen Region: 220-335
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 220-335 of human CADM2 (NP_001161147.1).
Immunogen Sequence: NATPQVAMQVLEIHYTPSVK IIPSTPFPQEGQPLILTCES KGKPLPEPVLWTKDGGELPD PDRMVVSGRELNILFLNKTD NGTYRCEATNTIGQSSAEYV LIVHDPNALAGQNGPD
Function Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. Isoform 5: (Microbial infection) Induces cell fusion in neuron infected by a neuropathogenic strain of measles.Interacts with measles hemagglutinin to trigger hyperfusogenic F-mediated membrane fusion and presumably transsynaptic cell-to-cell transmission of the virus.
Protein Name Cell Adhesion Molecule 2
Immunoglobulin Superfamily Member 4d
Igsf4d
Nectin-Like Protein 3
Necl-3
Synaptic Cell Adhesion Molecule 2
Syncam 2
Database Links Reactome: R-HSA-418990
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Synapse
Cell Projection
Axon
Found In The Axoplasm Of Myelinated Axons
Alternative Antibody Names Anti-Cell Adhesion Molecule 2 antibody
Anti-Immunoglobulin Superfamily Member 4d antibody
Anti-Igsf4d antibody
Anti-Nectin-Like Protein 3 antibody
Anti-Necl-3 antibody
Anti-Synaptic Cell Adhesion Molecule 2 antibody
Anti-Syncam 2 antibody
Anti-CADM2 antibody
Anti-IGSF4D antibody
Anti-NECL3 antibody

Information sourced from Uniprot.org

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