Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CADM2 (220-335) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CADM2 |
Gene ID: |
253559 |
Uniprot ID: |
CADM2_HUMAN |
Immunogen Region: |
220-335 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 220-335 of human CADM2 (NP_001161147.1). |
Immunogen Sequence: |
NATPQVAMQVLEIHYTPSVK IIPSTPFPQEGQPLILTCES KGKPLPEPVLWTKDGGELPD PDRMVVSGRELNILFLNKTD NGTYRCEATNTIGQSSAEYV LIVHDPNALAGQNGPD |
Function | Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. |
Protein Name | Cell Adhesion Molecule 2Immunoglobulin Superfamily Member 4dIgsf4dNectin-Like Protein 3Necl-3Synaptic Cell Adhesion Molecule 2Syncam 2 |
Database Links | Reactome: R-HSA-418990 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynapseCell ProjectionAxonFound In The Axoplasm Of Myelinated Axons |
Alternative Antibody Names | Anti-Cell Adhesion Molecule 2 antibodyAnti-Immunoglobulin Superfamily Member 4d antibodyAnti-Igsf4d antibodyAnti-Nectin-Like Protein 3 antibodyAnti-Necl-3 antibodyAnti-Synaptic Cell Adhesion Molecule 2 antibodyAnti-Syncam 2 antibodyAnti-CADM2 antibodyAnti-IGSF4D antibodyAnti-NECL3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance