| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BTBD1 (C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BTBD1 |
| Gene ID: |
53339 |
| Uniprot ID: |
BTBD1_HUMAN |
| Immunogen Region: |
C-Term |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human BTBD1 (NP_079514.1). |
| Immunogen Sequence: |
CDGTANTFRVMFKEPIEILP NVCYTACATLKGPDSHYGTK GLKKVVHETPAASKTVFFFF SSPGNNNGTSIEDGQIPEII FYT |
| Tissue Specificity | Ubiquitous.highest levels in testes, heart and skeletal muscle. |
| Function | Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis. |
| Protein Name | Btb/Poz Domain-Containing Protein 1Hepatitis C Virus Ns5a-Transactivated Protein 8Hcv Ns5a-Transactivated Protein 8 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmLocalizes To Punctate Or Elongated Cytoplasmic Bodies |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 1 antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 8 antibodyAnti-Hcv Ns5a-Transactivated Protein 8 antibodyAnti-BTBD1 antibodyAnti-C15orf1 antibodyAnti-NS5ATP8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
