| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BCAN |
| Gene ID: |
63827 |
| Uniprot ID: |
PGCB_HUMAN |
| Immunogen Region: |
762-911 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 762-911 of human BCAN (NP_068767.3). |
| Immunogen Sequence: |
VPLLYENWNPGQPDSYFLSG ENCVVMVWHDQGQWSDVPCN YHLSYTCKMGLVSCGPPPEL PLAQVFGRPRLRYEVDTVLR YRCREGLAQRNLPLIRCQEN GRWEAPQISCVPRRPARALH PEEDPEGRQGRLLGRWKALL IPPSSPMPGP |
| Tissue Specificity | Expressed in the retina, specifically in the inner nuclear layer, inner plexiform layer and ganglion cell layer (at protein level). Detected in cerebrospinal fluid (at protein level). Detected in urine (at protein level). |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate. O-glycosylated with a core 1 or possibly core 8 glycan. |
| Function | May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. |
| Protein Name | Brevican Core ProteinBrain-Enriched Hyaluronan-Binding ProteinBehabChondroitin Sulfate Proteoglycan 7 |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | SecretedIsoform 1: SecretedExtracellular SpaceExtracellular MatrixIsoform 2: MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Brevican Core Protein antibodyAnti-Brain-Enriched Hyaluronan-Binding Protein antibodyAnti-Behab antibodyAnti-Chondroitin Sulfate Proteoglycan 7 antibodyAnti-BCAN antibodyAnti-BEHAB antibodyAnti-CSPG7 antibodyAnti-UNQ2525 antibodyAnti-PRO6018 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
