| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ASMT (1-298) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ASMT |
| Gene ID: |
438 |
| Uniprot ID: |
ASMT_HUMAN |
| Immunogen Region: |
1-298 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human ASMT (NP_001164510.1). |
| Immunogen Sequence: |
MGSSEDQAYRLLNDYANGFM VSQVLFAACELGVFDLLAEA PGPLDVAAVAAGVRASAHGT ELLLDICVSLKLLKVETRGG KAFYRNTELSSDYLTTVSPT SQCSMLKYMGRTSYRCWGHL ADAVREGRNQYLETFGVPAE ELFTAIYRSEGERLQFMQAL QEVWSVNGRSVLTAFDLSVF PLMCDLGGDFFKDPLPEADL YILARVLHDWADGKCSHLLE RIYHTCKPGGGILVIESLL |
| Tissue Specificity | Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level, and not at the protein level. |
| Function | Isoform 1: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2: Does not show Acetylserotonin O-methyltransferase activity. Isoform 3: Does not show Acetylserotonin O-methyltransferase activity. |
| Protein Name | Acetylserotonin O-MethyltransferaseHydroxyindole O-MethyltransferaseHiomt |
| Database Links | Reactome: R-HSA-209931 |
| Alternative Antibody Names | Anti-Acetylserotonin O-Methyltransferase antibodyAnti-Hydroxyindole O-Methyltransferase antibodyAnti-Hiomt antibodyAnti-ASMT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
