• Western blot analysis of lysates from Jurkat cells, using APOBEC3A Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of Jurkat cells using APOBEC3A Polyclonal Antibody

Anti-APOBEC3A antibody (27-76 aa) (STJ91635)

SKU:
STJ91635

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNA dC->dU-editing enzyme APOBEC-3A (27-76 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOBEC3A
Gene ID: 100913187/200315
Uniprot ID: ABC3A_HUMAN
Immunogen Region: 27-76 aa
Specificity: APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human APOBEC3A at the amino acid range 27-76
Function DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Protein Name Dna Dc->Du-Editing Enzyme Apobec-3a
A3a
Phorbolin-1
Database Links Reactome: R-HSA-72200
Reactome: R-HSA-75094
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Dna Dc->Du-Editing Enzyme Apobec-3a antibody
Anti-A3a antibody
Anti-Phorbolin-1 antibody
Anti-APOBEC3A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance