• Western blot analysis of the lysates from HT-29 cells using AGTRL1 antibody.
  • Western blot analysis of lysates from HT-29 cells, using AGTRL1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Immunofluorescence analysis of MCF7 cells, using AGTRL1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of 293 cells using APLNR Polyclonal Antibody

Anti-APLNR antibody (141-190 aa) (STJ91630)

SKU:
STJ91630

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Apelin receptor (141-190 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APLNR
Gene ID: 187
Uniprot ID: APJ_HUMAN
Immunogen Region: 141-190 aa
Specificity: APLNR Polyclonal Antibody detects endogenous levels of APLNR protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human AGTRL1 at the amino acid range 141-190
Function Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. Also plays a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.may be involved in the development of AIDS dementia.
Protein Name Apelin Receptor
Angiotensin Receptor-Like 1
G-Protein Coupled Receptor Apj
G-Protein Coupled Receptor Hg11
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
After Exposure To Apelin (Apln)
Internalized From The Cell Surface Into An Endosomal Recycling Compartment
From Where It Is Recycled To The Cell Membrane
After Exposure To Apelin Receptor Early Endogenous Ligand (Apela)
Alternative Antibody Names Anti-Apelin Receptor antibody
Anti-Angiotensin Receptor-Like 1 antibody
Anti-G-Protein Coupled Receptor Apj antibody
Anti-G-Protein Coupled Receptor Hg11 antibody
Anti-APLNR antibody
Anti-AGTRL1 antibody
Anti-APJ antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance