| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AP1S1 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AP1S1 |
| Gene ID: |
1174 |
| Uniprot ID: |
AP1S1_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human AP1S1 (NP_001274.1). |
| Immunogen Sequence: |
MMRFMLLFSRQGKLRLQKWY LATSDKERKKMVRELMQVVL ARKPKMCSFLEWRDLKVVYK RYASLYFCCAIEGQDNELIT LELIHRYVELLDKYFGSVCE LDIIFNFEKAYFILDEFLMG |
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Protein Name | Ap-1 Complex Subunit Sigma-1aAdaptor Protein Complex Ap-1 Subunit Sigma-1aAdaptor-Related Protein Complex 1 Subunit Sigma-1aClathrin Assembly Protein Complex 1 Sigma-1a Small ChainClathrin Coat Assembly Protein Ap19Golgi Adaptor Ha1/Ap1 Adaptin Sigma-1a SubunitHa1 19 Kda SubunitSigma 1a Subunit Of Ap-1 ClathrinSigma-Adaptin 1aSigma1a-Adaptin |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Sigma-1a antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Sigma-1a antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Sigma-1a antibodyAnti-Clathrin Assembly Protein Complex 1 Sigma-1a Small Chain antibodyAnti-Clathrin Coat Assembly Protein Ap19 antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Sigma-1a Subunit antibodyAnti-Ha1 19 Kda Subunit antibodyAnti-Sigma 1a Subunit Of Ap-1 Clathrin antibodyAnti-Sigma-Adaptin 1a antibodyAnti-Sigma1a-Adaptin antibodyAnti-AP1S1 antibodyAnti-AP19 antibodyAnti-CLAPS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
