| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ANGPT4 (25-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANGPT4 |
| Gene ID: |
51378 |
| Uniprot ID: |
ANGP4_HUMAN |
| Immunogen Region: |
25-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-260 of human ANGPT4 (NP_057069.1). |
| Immunogen Sequence: |
TRQEADRGCETLVVQHGHCS YTFLLPKSEPCPPGPEVSRD SNTLQRESLANPLHLGKLPT QQVKQLEQALQNNTQWLKKL ERAIKTILRSKLEQVQQQMA QNQTAPMLELGTSLLNQTTA QIRKLTDMEAQLLNQTSRMD AQMPETFLSTNKLENQLLLQ RQKLQQLQGQNSALEKRLQA LETKQQEELASILSKKAKLL NTLSRQSAALTNIERGLRGV RHNSSLLQDQQHSLRQ |
| Tissue Specificity | Highly expressed in the lung with much lower levels found in other tissues. |
| Function | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. |
| Protein Name | Angiopoietin-4Ang-4Angiopoietin-3Ang-3 |
| Database Links | Reactome: R-HSA-210993 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Angiopoietin-4 antibodyAnti-Ang-4 antibodyAnti-Angiopoietin-3 antibodyAnti-Ang-3 antibodyAnti-ANGPT4 antibodyAnti-ANG3 antibodyAnti-ANG4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
