| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADGRD1 |
| Gene ID: | 283383 |
| Uniprot ID: | AGRD1_HUMAN |
| Immunogen Region: | 805-874 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 805-874 of human ADGRD1 (NP_942122.2). |
| Immunogen Sequence: | FHCLLNSEVRAAFKHKTKVW SLTSSSARTSNAKPFHSDLM NGTRPGMASTKLSPWDKSSH SAHRVDLSAV |
| Tissue Specificity | Up-regulated in CD133(+) cell population of glioblastoma. |
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. |
| Function | Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma. |
| Protein Name | Adhesion G-Protein Coupled Receptor D1G-Protein Coupled Receptor 133G-Protein Coupled Receptor Pgr25 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G-Protein Coupled Receptor D1 antibodyAnti-G-Protein Coupled Receptor 133 antibodyAnti-G-Protein Coupled Receptor Pgr25 antibodyAnti-ADGRD1 antibodyAnti-GPR133 antibodyAnti-PGR25 antibody |
Information sourced from Uniprot.org