TMPRSS2 and COVID-19

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TMPRSS2 and SARS-CoV-2 research

What is TMPRSS2?

Transmembrane protease serine 2 (TMPRSS2) is an enzyme found in the human body, that is encoded by the TMPRSS2 gene.  This serine protease is anchored in the plasma membrane and participates in proteolytic cascades, responsible for normal prostate function. 

TMPRSS2 and COVID-19 infection.

Several coronaviruses, SARS-CoV-1, MERS-CoV and most recently SARS-CoV-2 have been found to be activated by this serine protease. Because of this, they can be easily inhibited by TMPRSS2 inhibitors. Furthermore, SARS-CoV-2 uses this protease for its S protein priming, making TMPRSS2 an important target for research. 

We offer a large variety of TMPRSS2 antibodies, proteins and ELISA kits to support your research.

Antibodies

Image Name Host Application Clonality
Anti-TMPRSS2 antibody (STJ195891) Rabbit WB Polyclonal
Anti-TMPRSS2-antibody [ARC1439] (STJ11102428) Rabbit WB, IHC Monoclonal
Anti-TMPRSS2 Antibody (STJ71393) Goat Pep-ELISA, WB Polyclonal

ELISA kits

Proteins