TMPRSS2 and COVID-19
TMPRSS2 and SARS-CoV-2 research
What is TMPRSS2?
Transmembrane protease serine 2 (TMPRSS2) is an enzyme found in the human body, that is encoded by the TMPRSS2 gene. This serine protease is anchored in the plasma membrane and participates in proteolytic cascades, responsible for normal prostate function.
TMPRSS2 and COVID-19 infection.
Several coronaviruses, SARS-CoV-1, MERS-CoV and most recently SARS-CoV-2 have been found to be activated by this serine protease. Because of this, they can be easily inhibited by TMPRSS2 inhibitors. Furthermore, SARS-CoV-2 uses this protease for its S protein priming, making TMPRSS2 an important target for research.
We offer a large variety of TMPRSS2 antibodies, proteins and ELISA kits to support your research.
Antibodies
| Image | Name | Host | Application | Clonality |
|---|---|---|---|---|
 |
Anti-TMPRSS2 antibody (STJ195891) | Rabbit | WB | Polyclonal |
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Anti-TMPRSS2-antibody [ARC1439] (STJ11102428) | Rabbit | WB, IHC | Monoclonal |
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Anti-TMPRSS2 Antibody (STJ71393) | Goat | Pep-ELISA, WB | Polyclonal |
ELISA kits
| Model | Name |
|---|---|
| STJE0002955 | Human TMPRSS2 (Transmembrane Protease, Serine 2) Sandwich ELISA Kit |
| STJC0000631 | Human TMPRSS2 (Transmembrane Protease, Serine 2) CLIA Kit |
Proteins
| Model | Name |
|---|---|
| STJP000026 | Human ACE2 Protein |