| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
ROR2 Blocking Peptide for STJ502830 is synthetically produced from the 900-943 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ROR2 |
| Gene ID: |
4920 |
| Uniprot ID: |
ROR2_HUMAN |
| Immunogen Region: |
900-943 |
| Specificity: |
This blocking peptide is recommended for use in combination with ROR2 antibody, STJ502830 |
| Immunogen: |
Synthetic peptide taken within amino acid region 900-943 on human ROR2 protein. |
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. |
| Peptide Name | Tyrosine-Protein Kinase Transmembrane Receptor Ror2Neurotrophic Tyrosine Kinase - Receptor-Related 2 |
| Database Links | Reactome: R-HSA-4086400Reactome: R-HSA-5140745 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Tyrosine-Protein Kinase Transmembrane Receptor Ror2 proteinNeurotrophic Tyrosine Kinase - Receptor-Related 2 proteinROR2 proteinNTRKR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
