| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.117ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This PRDX1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Prdx1 |
| Gene ID: |
117254 |
| Uniprot ID: |
PRDX1_RAT |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated on Thr-90 during the M-phase, which leads to a decrease in enzymatic activity. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. |
| Protein Name | Peroxiredoxin-1Hbp23Heme-Binding 23 Kda ProteinThioredoxin Peroxidase 2Thioredoxin-Dependent Peroxide Reductase 2Thioredoxin-Dependent Peroxiredoxin 1 |
| Database Links | Reactome: R-RNO-3299685Reactome: -RNO-5628897Reactome: -RNO-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Peroxiredoxin-1 ELISA kitHbp23 ELISA kitHeme-Binding 23 Kda Protein ELISA kitThioredoxin Peroxidase 2 ELISA kitThioredoxin-Dependent Peroxide Reductase 2 ELISA kitThioredoxin-Dependent Peroxiredoxin 1 ELISA kitPrdx1 ELISA kitTdpx2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
