| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.055ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This PMP22 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Pmp22 |
| Gene ID: |
24660 |
| Uniprot ID: |
PMP22_RAT |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Found exclusively in the peripheral nervous system. Present in both myelinating and nonmyelinating Schwann cells. Found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). |
| Post Translational Modifications | Ubiquitinated by the DCX(DCAF13) E3 ubiquitin ligase complex, leading to its degradation. |
| Function | Might be involved in growth regulation, and in myelinization in the peripheral nervous system. |
| Protein Name | Peripheral Myelin Protein 22Pmp-22Protein Cd25Sr13 Myelin ProteinSchwann Cell Membrane GlycoproteinSag |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Peripheral Myelin Protein 22 ELISA kitPmp-22 ELISA kitProtein Cd25 ELISA kitSr13 Myelin Protein ELISA kitSchwann Cell Membrane Glycoprotein ELISA kitSag ELISA kitPmp22 ELISA kitCd25 ELISA kitPmp-22 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
