| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
33pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This NLGN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Nlgn1 |
| Gene ID: |
116647 |
| Uniprot ID: |
NLGN1_RAT |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in brain, almost exclusively in neurons, and spinal chord. Detected in pancreas islet beta cells. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. The protein is involved in nervous system development. |
| Protein Name | Neuroligin-1Neuroligin I |
| Database Links | Reactome: R-RNO-6794361 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPostsynaptic DensitySynaptic CleftSynaptic Cell MembraneEnriched In Synaptic Plasma Membranes And Clustered In Synaptic Clefts And Postsynaptic DensitiesColocalized With Dlg4/Psd-95 And Grin1/Nmdar1 |
| Alternative ELISA Names | Neuroligin-1 ELISA kitNeuroligin I ELISA kitNlgn1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
