| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
27pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This MGMT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Mgmt |
| Gene ID: |
25332 |
| Uniprot ID: |
MGMT_RAT |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
| Protein Name | Methylated-Dna--Protein-Cysteine Methyltransferase6-O-Methylguanine-Dna MethyltransferaseMgmtO-6-Methylguanine-Dna-Alkyltransferase |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Methylated-Dna--Protein-Cysteine Methyltransferase ELISA kit6-O-Methylguanine-Dna Methyltransferase ELISA kitMgmt ELISA kitO-6-Methylguanine-Dna-Alkyltransferase ELISA kitMgmt ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
