| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.109ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This IL8Rb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Cxcr2 |
| Gene ID: |
29385 |
| Uniprot ID: |
CXCR2_RAT |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated upon ligand binding.which is required for desensitization. |
| Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
| Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Gro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BCd Antigen Cd182 |
| Database Links | Reactome: R-RNO-380108Reactome: -RNO-418594Reactome: -RNO-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | C-X-C Chemokine Receptor Type 2 ELISA kitCxc-R2 ELISA kitCxcr-2 ELISA kitGro/Mgsa Receptor ELISA kitHigh Affinity Interleukin-8 Receptor B ELISA kitIl-8r B ELISA kitCd Antigen Cd182 ELISA kitCxcr2 ELISA kitIl8rb ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
