Rat ERb (Estrogen Receptor Beta) Sandwich ELISA Kit Kit (STJE0008688)

Rat ERb (Estrogen Receptor Beta) Sandwich ELISA Kit Kit (STJE0008688)

SKU:
STJE0008688
€570.63 - €781.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.112ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This ERb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Esr2
Gene ID: 25149
Uniprot ID: ESR2_RAT
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in the CA1 region of the hippocampus, expression decreases with age (at protein level). Expressed in prostate, ovary, lung, liver, kidney, fat, bone, brain, uterus and testis.
Post Translational Modifications Phosphorylation at Ser-87 and Ser-105 recruits NCOA1.
Function Isoform 1: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform 2: Lacks ligand binding affinity and suppresses ESR1/ER-alpha and ESR2 isoform 1/ER-beta1 mediated transcriptional activation and may act as a dominant negative regulator of estrogen action. Isoform 3: Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain. Isoform 4: Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain.
Protein Name Estrogen Receptor Beta
Er-Beta
Nuclear Receptor Subfamily 3 Group A Member 2
Database Links Reactome: R-RNO-1257604
Reactome: -RNO-383280
Reactome: -RNO-6811558
Reactome: -RNO-8939211
Reactome: -RNO-9009391
Cellular Localisation Nucleus
Alternative ELISA Names Estrogen Receptor Beta ELISA kit
Er-Beta ELISA kit
Nuclear Receptor Subfamily 3 Group A Member 2 ELISA kit
Esr2 ELISA kit
Erbeta ELISA kit
Nr3a2 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0015067 Rat ERb (Estrogen Receptor Beta) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015067) Rat ELISA
STJE0008684 Rat ERa (Estrogen Receptor Alpha) Sandwich ELISA Kit Kit (STJE0008684) Rat ELISA
STJE0008705 Rat ERRa (Estrogen Related Receptor Alpha) Sandwich ELISA Kit Kit (STJE0008705) Rat ELISA
STJE0015063 Rat ERa (Estrogen Receptor Alpha) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015063) Rat ELISA
STJE0006964 Rat ADRb2 (Adrenergic Receptor Beta 2) Sandwich ELISA Kit Kit (STJE0006964) Rat ELISA
!