| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
2.19pg/mL |
| Detection Limit: |
7.81-500pg/mL |
| Short Description: |
This EDN1 Competitive ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
2.5 hrs |
| Gene Symbol: |
Edn1 |
| Gene ID: |
24323 |
| Uniprot ID: |
EDN1_RAT |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor. |
| Protein Name | Endothelin-1Et-1Preproendothelin-1Ppet1 Cleaved Into - Big Endothelin-1 |
| Database Links | Reactome: R-RNO-375276Reactome: -RNO-416476 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Endothelin-1 ELISA kitEt-1 ELISA kitPreproendothelin-1 ELISA kitPpet1 Cleaved Into - Big Endothelin-1 ELISA kitEdn1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
