| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
1.24ng/mL |
| Detection Limit: |
3.12-200ng/mL |
| Short Description: |
This cADPRH Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Cd38 |
| Gene ID: |
25668 |
| Uniprot ID: |
CD38_RAT |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Spleen, liver, heart, thymus, thyroid gland, ileum, colon, cerebellum, salivary gland, adrenal gland, jejunum, islets of Langerhans and osteoclasts. |
| Post Translational Modifications | |
| Function | Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion, the latter a Ca(2+) mobilizer. Also has cADPR hydrolase activity. Regulates osteoclastic bone resorption, probably via production of cyclic ADP-ribose and triggering of a cytosolic calcium ion signal through ryanodine receptor activation. |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 12'-Phospho-Adp-Ribosyl Cyclase2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase2'-Phospho-Cyclic-Adp-Ribose TransferaseAdp-Ribosyl Cyclase 1Adprc 1Cd38hCyclic Adp-Ribose Hydrolase 1Cadpr Hydrolase 1Cd Antigen Cd38 |
| Database Links | Reactome: R-RNO-196807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative ELISA Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 ELISA kit2'-Phospho-Adp-Ribosyl Cyclase ELISA kit2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase ELISA kit2'-Phospho-Cyclic-Adp-Ribose Transferase ELISA kitAdp-Ribosyl Cyclase 1 ELISA kitAdprc 1 ELISA kitCd38h ELISA kitCyclic Adp-Ribose Hydrolase 1 ELISA kitCadpr Hydrolase 1 ELISA kitCd Antigen Cd38 ELISA kitCd38 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
