• Rat Alk-Smase (Alkaline Sphingomyelinase) Sandwich ELISA Kit Ready-To-Use (STJE0013451)

Rat Alk-Smase (Alkaline Sphingomyelinase) Sandwich ELISA Kit Ready-To-Use (STJE0013451)

SKU:
STJE0013451

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.043ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This Alk-Smase Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Enpp7
Gene ID: 303729
Uniprot ID: ENPP7_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Detected in small intestine (at protein level). Highly expressed in the jejunum.
Post Translational Modifications N-glycosylated.required for activity and transport to the plasma membrane.
Function Choline-specific phosphodiesterase that hydrolyzes sphingomyelin (SM) releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract. Has also phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation. Does not have nucleotide pyrophosphatase activity. May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen.
Protein Name Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 7
E-Npp 7
Npp-7
Alkaline Sphingomyelin Phosphodiesterase
Intestinal Alkaline Sphingomyelinase
Alk-Smase
Database Links Reactome: R-RNO-1660662
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
The Catalytic Domain Is Released Into The Extracellular Medium When Cells Are Treated With Trypsin
Localized At The Surface Of The Microvillar Membrane In Small Intestine Enterocytes
And In Endosome-Like Structures Situated Beneath The Microvillar Membrane
And In Golgi Complex
Alternative ELISA Names Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 7 ELISA kit
E-Npp 7 ELISA kit
Npp-7 ELISA kit
Alkaline Sphingomyelin Phosphodiesterase ELISA kit
Intestinal Alkaline Sphingomyelinase ELISA kit
Alk-Smase ELISA kit
Enpp7 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance