| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse uPAR/PLAUR/CD87-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
| Formulation: |
Supplied as a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Mouse uPAR isoform 1, His Tag immobilized on CM5 Chip can bind Human PLAU, His Tag with an affinity constant of 5.87 nM as determined in SPR assay (Biacore T200). |
| Gene Symbol: |
Plaur |
| Gene ID: |
18793 |
| Uniprot ID: |
UPAR_MOUSE |
| Immunogen Region: |
Leu24-Gly298 |
| Immunogen: |
Recombinant Mouse uPAR/PLAUR/CD87 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu24-Gly298) of mouse uPAR/PLAUR/CD87 (Accession #NP_035243.1) fused with 6×His, Avi tag at the C-terminus. |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. |
| Protein Name | Urokinase Plasminogen Activator Surface ReceptorU-ParUparCd Antigen Cd87 |
| Database Links | Reactome: R-MMU-162791Reactome: -MMU-6798695Reactome: -MMU-75205 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
| Alternative Protein Names | Urokinase Plasminogen Activator Surface Receptor proteinU-Par proteinUpar proteinCd Antigen Cd87 proteinPlaur protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
