| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse TNFRSF18/CD357-C-Fc & His protein was developed from hek293 cells and has a target region of C-Fc & His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Tnfrsf18 |
| Gene ID: |
21936 |
| Uniprot ID: |
TNR18_MOUSE |
| Immunogen Region: |
Ser22-His153 |
| Immunogen: |
Recombinant Mouse TNFRSF18/CD357 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Ser22-His153) of mouse GITR (Accession #O35714) fused with an Fc, 6xHis tag at the C-terminus. |
| Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 18Glucocorticoid-Induced Tnfr-Related ProteinCd Antigen Cd357 |
| Database Links | Reactome: R-MMU-5669034 |
| Cellular Localisation | Isoform A: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform B: Cell MembraneIsoform C: Cell MembraneIsoform D: Secreted |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 18 proteinGlucocorticoid-Induced Tnfr-Related Protein proteinCd Antigen Cd357 proteinTnfrsf18 proteinGitr protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
