Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.113ng/mL |
Detection Limit: |
0.312-20ng/mL |
Short Description: |
This TMPRSS2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
Tmprss2 |
Gene ID: |
50528 |
Uniprot ID: |
TMPS2_MOUSE |
Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Larynx, trachea and bronchi, lung, prostate and kidney. |
Post Translational Modifications | Proteolytically processed.by an autocatalytic mechanism. |
Function | Plasma membrane-anchored serine protease that cleaves at arginine residues. Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia. (Microbial infection) Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9) and is involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity. |
Protein Name | Transmembrane Protease Serine 2EpitheliasinPlasmic Transmembrane Protein X Cleaved Into - Transmembrane Protease Serine 2 Non-Catalytic Chain - Transmembrane Protease Serine 2 Catalytic Chain |
Database Links | |
Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTransmembrane Protease Serine 2 Catalytic Chain: SecretedActivated By Cleavage And Secreted |
Alternative ELISA Names | Transmembrane Protease Serine 2 ELISA kitEpitheliasin ELISA kitPlasmic Transmembrane Protein X Cleaved Into - Transmembrane Protease Serine 2 Non-Catalytic Chain - Transmembrane Protease Serine 2 Catalytic Chain ELISA kitTmprss2 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance