| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
4.1pg/mL |
| Detection Limit: |
9.37-600pg/mL |
| Short Description: |
This REG3b Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Reg3b |
| Gene ID: |
18489 |
| Uniprot ID: |
REG3B_MOUSE |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas. |
| Post Translational Modifications | Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity. |
| Function | Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. Acts as a hormone in response to different stimuli. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways. In pancreas, is able stimulate cell proliferation. |
| Protein Name | Regenerating Islet-Derived Protein 3-BetaReg-3-BetaPancreatitis-Associated Protein 1Regenerating Islet-Derived Protein Iii-BetaReg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form |
| Database Links | Reactome: R-MMU-6803157 |
| Cellular Localisation | SecretedFound In The Apical Region Of Pancreatic Acinar Cells |
| Alternative ELISA Names | Regenerating Islet-Derived Protein 3-Beta ELISA kitReg-3-Beta ELISA kitPancreatitis-Associated Protein 1 ELISA kitRegenerating Islet-Derived Protein Iii-Beta ELISA kitReg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form ELISA kitReg3b ELISA kitPap ELISA kitPap1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
