Mouse Pro-EGF protein (Recombinant) (C-His) (STJP001125)

SKU:
STJP001125

Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse Pro-EGF-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse pro-EGF at 200 ng/mL (100 Mu L/well) can bind Recombinant Human EGFR with a linear range of 5-12 ng/mL.
Gene Symbol: Egf
Gene ID: 13645
Uniprot ID: EGF_MOUSE
Immunogen Region: Trp29-Arg1029
Immunogen: Recombinant Mouse Pro-EGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp29-Arg1029) of mouse Pro-EGF (Accession #NP_034243.2) fused with a 6×His tag at the C-terminus.
Function EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
Protein Name Pro-Epidermal Growth Factor
Egf Cleaved Into - Epidermal Growth Factor
Database Links Reactome: R-MMU-114608
Reactome: -MMU-1227986
Reactome: -MMU-1236394
Reactome: -MMU-1250196
Reactome: -MMU-1257604
Reactome: -MMU-177929
Reactome: -MMU-179812
Reactome: -MMU-180292
Reactome: -MMU-180336
Reactome: -MMU-182971
Reactome: -MMU-1963642
Reactome: -MMU-212718
Reactome: -MMU-5673001
Reactome: -MMU-6785631
Reactome: -MMU-6811558
Reactome: -MMU-8847993
Reactome: -MMU-8856825
Reactome: -MMU-8856828
Reactome: -MMU-8863795
Reactome: -MMU-9009391
Reactome: -MMU-9013507
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Pro-Epidermal Growth Factor protein
Egf Cleaved Into - Epidermal Growth Factor protein
Egf protein

Information sourced from Uniprot.org

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