| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.108ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This PRDX4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Prdx4 |
| Gene ID: |
53381 |
| Uniprot ID: |
PRDX4_MOUSE |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) and sulphonic acid (C(P)-SO3H) instead of its condensation to a disulfide bond. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. |
| Protein Name | Peroxiredoxin-4Antioxidant Enzyme Aoe372Peroxiredoxin IvPrx-IvThioredoxin Peroxidase Ao372Thioredoxin-Dependent Peroxide Reductase A0372Thioredoxin-Dependent Peroxiredoxin 4 |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumNot Secreted |
| Alternative ELISA Names | Peroxiredoxin-4 ELISA kitAntioxidant Enzyme Aoe372 ELISA kitPeroxiredoxin Iv ELISA kitPrx-Iv ELISA kitThioredoxin Peroxidase Ao372 ELISA kitThioredoxin-Dependent Peroxide Reductase A0372 ELISA kitThioredoxin-Dependent Peroxiredoxin 4 ELISA kitPrdx4 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
