Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Mouse OSM/Oncostatin-M-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | Osm |
Gene ID: | 18413 |
Uniprot ID: | ONCM_MOUSE |
Immunogen Region: | Ala24-Gln207 |
Immunogen: | Mus musculus (Mouse) |
Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. |
Protein Name | Oncostatin-MOsm |
Database Links | Reactome: R-MMU-6788467 |
Cellular Localisation | Secreted |
Alternative Protein Names | Oncostatin-M proteinOsm proteinOsm protein |
Information sourced from Uniprot.org