• Mouse NUCB2 (Nucleobindin 2) Sandwich ELISA Kit Ready-To-Use (STJE0017529)

Mouse NUCB2 (Nucleobindin 2) Sandwich ELISA Kit Ready-To-Use (STJE0017529)

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STJE0017529

£491.50 - £674.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 12.5pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description: This NUCB2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Nucb2
Gene ID: 53322
Uniprot ID: NUCB2_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Found in liver, heart, thymus, muscle, intestine, kidney, lung, spleen and throughout the brain, in cerebral cortex, hippocampus, hypothalamus and medulla oblongata. Nucb2 and necdin levels were higher in postmitotic neurons.
Post Translational Modifications
Function Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Protein Name Nucleobindin-2
Dna-Binding Protein Nefa
Prepronesfatin Cleaved Into - Nesfatin-1
Database Links
Cellular Localisation Cytoplasm
Perikaryon
Endoplasmic Reticulum
Golgi Apparatus
Nucleus Envelope
Membrane
Peripheral Membrane Protein
Secreted
In Dendrites And Perikarya Of Brain Neurons
Abundant In The Er Cisternae And Nuclear Envelope
But Not Detected In Golgi
Mitochondria Or Nucleoplasm In Neurons
In Cell Culture
Cytoplasmic And Secreted
Nesfatin-1: Secreted
Alternative ELISA Names Nucleobindin-2 ELISA kit
Dna-Binding Protein Nefa ELISA kit
Prepronesfatin Cleaved Into - Nesfatin-1 ELISA kit
Nucb2 ELISA kit
Nefa ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance