• Mouse NOX4 (Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4) Sandwich ELISA Kit (STJE0011025)

Mouse NOX4 (Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4) Sandwich ELISA Kit (STJE0011025)

SKU:
STJE0011025

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.067ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This NOX4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Nox4
Gene ID: 50490
Uniprot ID: NOX4_MOUSE
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung.
Post Translational Modifications N-glycosylation is required for the function.
Function Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Protein Name Nadph Oxidase 4
Kidney Oxidase-1
Kox-1
Kidney Superoxide-Producing Nadph Oxidase
Renal Nad(Ph-Oxidase
Superoxide-Generating Nadph Oxidase 4
Database Links Reactome: R-MMU-3299685
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Cell Junction
Focal Adhesion
Cell Membrane
May Localize To Plasma Membrane And Focal Adhesions
Alternative ELISA Names Nadph Oxidase 4 ELISA kit
Kidney Oxidase-1 ELISA kit
Kox-1 ELISA kit
Kidney Superoxide-Producing Nadph Oxidase ELISA kit
Renal Nad(Ph-Oxidase ELISA kit
Superoxide-Generating Nadph Oxidase 4 ELISA kit
Nox4 ELISA kit
Renox ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance