| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.054ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This MTTP Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Mttp |
| Gene ID: |
17777 |
| Uniprot ID: |
MTP_MOUSE |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Isoform 1: Mainly expressed in the intestine and the liver, and at lower levels in white and brown fat cells. Expressed in heart. Isoform 2: Ubiquitous, and is the major isoform in hematopoietic cells and adipocytes. |
| Post Translational Modifications | Isoform 2: Cleaved by signal peptidase between residues Gln-33 and Asn-34. |
| Function | Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins. Isoform 2: Critical for the development of natural killer T (NKT) cells. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. |
| Protein Name | Microsomal Triglyceride Transfer Protein Large Subunit |
| Database Links | Reactome: R-MMU-8866423Reactome: -MMU-8963888Reactome: -MMU-8964041 |
| Cellular Localisation | Endoplasmic ReticulumIsoform 1: Endoplasmic ReticulumGolgi ApparatusColocalizes With P4hb/Pdi In The Endoplasmic ReticulumIsoform 2: Endoplasmic Reticulum |
| Alternative ELISA Names | Microsomal Triglyceride Transfer Protein Large Subunit ELISA kitMttp ELISA kitMtp ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
