| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.054ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This MRC2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Mrc2 |
| Gene ID: |
17534 |
| Uniprot ID: |
MRC2_MOUSE |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly expressed in heart, lung and kidney, but little or no expression in brain, thymus or adult liver. Expressed at highly endothelialized sites such as those in choroid plexus and kidney glomerulai as well as in chondrocytes in cartilaginous regions of the embryo. |
| Post Translational Modifications | Phosphorylated. |
| Function | May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). |
| Protein Name | C-Type Mannose Receptor 2Lectin LambdaMacrophage Mannose Receptor 2Cd Antigen Cd280 |
| Database Links | Reactome: R-MMU-1236978 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | C-Type Mannose Receptor 2 ELISA kitLectin Lambda ELISA kitMacrophage Mannose Receptor 2 ELISA kitCd Antigen Cd280 ELISA kitMrc2 ELISA kitKiaa0709 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
