• Mouse MRC2 (Mannose Receptor C Type 2) Sandwich ELISA Kit (STJE0010730)

Mouse MRC2 (Mannose Receptor C Type 2) Sandwich ELISA Kit (STJE0010730)

SKU:
STJE0010730

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.054ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This MRC2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Mrc2
Gene ID: 17534
Uniprot ID: MRC2_MOUSE
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in heart, lung and kidney, but little or no expression in brain, thymus or adult liver. Expressed at highly endothelialized sites such as those in choroid plexus and kidney glomerulai as well as in chondrocytes in cartilaginous regions of the embryo.
Post Translational Modifications Phosphorylated.
Function May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Protein Name C-Type Mannose Receptor 2
Lectin Lambda
Macrophage Mannose Receptor 2
Cd Antigen Cd280
Database Links Reactome: R-MMU-1236978
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names C-Type Mannose Receptor 2 ELISA kit
Lectin Lambda ELISA kit
Macrophage Mannose Receptor 2 ELISA kit
Cd Antigen Cd280 ELISA kit
Mrc2 ELISA kit
Kiaa0709 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance