• Mouse MASP1 (Mannose Associated Serine Protease 1) Sandwich ELISA Kit Ready-To-Use (STJE0016880)

Mouse MASP1 (Mannose Associated Serine Protease 1) Sandwich ELISA Kit Ready-To-Use (STJE0016880)

SKU:
STJE0016880

Shipping:
Free Shipping
Current Stock:
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.8ng/mL
Detection Limit: 2.34-150ng/mL
Short Description: This MASP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Masp1
Gene ID: 17174
Uniprot ID: MASP1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Protein of the plasma which is primarily expressed by liver.
Post Translational Modifications The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. N-glycosylated. Some N-linked glycan are of the complex-type. Autoproteolytic processing of the proenzyme produces the active enzyme composed on the heavy and the light chain held together by a disulfide bond. Isoform 1 but not isoform 2 is activated through autoproteolytic processing.
Function Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development.
Protein Name Mannan-Binding Lectin Serine Protease 1
Complement Factor Masp-3
Complement-Activating Component Of Ra-Reactive Factor
Mannose-Binding Lectin-Associated Serine Protease 1
Masp-1
Mannose-Binding Protein-Associated Serine Protease
Ra-Reactive Factor Serine Protease P100
Rarf
Serine Protease 5 Cleaved Into - Mannan-Binding Lectin Serine Protease 1 Heavy Chain - Mannan-Binding Lectin Serine Protease 1 Light Chain
Database Links Reactome: R-MMU-166662
Reactome: -MMU-166663
Reactome: -MMU-2855086
Reactome: -MMU-3000480
Cellular Localisation Secreted
Alternative ELISA Names Mannan-Binding Lectin Serine Protease 1 ELISA kit
Complement Factor Masp-3 ELISA kit
Complement-Activating Component Of Ra-Reactive Factor ELISA kit
Mannose-Binding Lectin-Associated Serine Protease 1 ELISA kit
Masp-1 ELISA kit
Mannose-Binding Protein-Associated Serine Protease ELISA kit
Ra-Reactive Factor Serine Protease P100 ELISA kit
Rarf ELISA kit
Serine Protease 5 Cleaved Into - Mannan-Binding Lectin Serine Protease 1 Heavy Chain - Mannan-Binding Lectin Serine Protease 1 Light Chain ELISA kit
Masp1 ELISA kit
Crarf ELISA kit
Masp3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance