| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.056ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This LPCAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Lpcat1 |
| Gene ID: |
210992 |
| Uniprot ID: |
PCAT1_MOUSE |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Predominantly expressed in lung where it is enriched in alveolar type II cells. Expressed at lower levels in spleen and brain. Also detected in erythroleukemic cells and reticulocytes. Weakly or not expressed in other tissues. |
| Post Translational Modifications | |
| Function | Exhibits both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Involved in the regulation of lipid droplet number and size. |
| Protein Name | Lysophosphatidylcholine Acyltransferase 1Lpc Acyltransferase 1Lpcat-1Lysopc Acyltransferase 1Mlpcat11-Acylglycerol-3-Phosphate O-Acyltransferase1-Acylglycerophosphocholine O-Acyltransferase1-Alkenylglycerophosphocholine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcetyl-Coa -Lyso-Platelet-Activating Factor AcetyltransferaseAcetyl-Coa -Lyso-Paf AcetyltransferaseLyso-Paf AcetyltransferaseLysopafatAcyltransferase-Like 2 |
| Database Links | Reactome: R-MMU-1482788Reactome: -MMU-1482925Reactome: -MMU-1483166Reactome: -MMU-1483191Reactome: -MMU-6798695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus MembraneCell MembraneLipid DropletMay Adopt A Monotopic Topology When Embedded In The Lipid Monolayer Of The Lipid DropletWith Both Termini Exposed To The Cytoplasm |
| Alternative ELISA Names | Lysophosphatidylcholine Acyltransferase 1 ELISA kitLpc Acyltransferase 1 ELISA kitLpcat-1 ELISA kitLysopc Acyltransferase 1 ELISA kitMlpcat1 ELISA kit1-Acylglycerol-3-Phosphate O-Acyltransferase ELISA kit1-Acylglycerophosphocholine O-Acyltransferase ELISA kit1-Alkenylglycerophosphocholine O-Acyltransferase ELISA kit1-Alkylglycerophosphocholine O-Acetyltransferase ELISA kitAcetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase ELISA kitAcetyl-Coa -Lyso-Paf Acetyltransferase ELISA kitLyso-Paf Acetyltransferase ELISA kitLysopafat ELISA kitAcyltransferase-Like 2 ELISA kitLpcat1 ELISA kitAytl2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
