• Mouse KRT18 (Keratin 18) Sandwich ELISA Kit (STJE0010224)

Mouse KRT18 (Keratin 18) Sandwich ELISA Kit (STJE0010224)

SKU:
STJE0010224

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 25pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This KRT18 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Krt18
Gene ID: 16668
Uniprot ID: K1C18_MOUSE
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Expressed in endoderm, intestinal epithelial cells and in most extraembryonic tissues.
Post Translational Modifications Phosphorylation increases by IL-6. Proteolytically cleaved by caspases during epithelial cell apoptosis. Cleavage occurs at Asp-231 by either caspase-3, caspas-6 or caspase-7. O-GlcNAcylation increases solubility, and decreases stability by inducing proteasomal degradation.
Function When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Protein Name Keratin - Type I Cytoskeletal 18
Cytokeratin Endo B
Keratin D
Cytokeratin-18
Ck-18
Keratin-18
K18
Database Links Reactome: R-MMU-6805567
Reactome: -MMU-6809371
Cellular Localisation Nucleus Matrix
Cytoplasm
Perinuclear Region
Nucleus
Nucleolus
Alternative ELISA Names Keratin - Type I Cytoskeletal 18 ELISA kit
Cytokeratin Endo B ELISA kit
Keratin D ELISA kit
Cytokeratin-18 ELISA kit
Ck-18 ELISA kit
Keratin-18 ELISA kit
K18 ELISA kit
Krt18 ELISA kit
Kerd ELISA kit
Krt1-18 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance