• Mouse IQGAP1 (IQ Motif Containing GTPase Activating Protein 1) Sandwich ELISA Kit (STJE0010044)

Mouse IQGAP1 (IQ Motif Containing GTPase Activating Protein 1) Sandwich ELISA Kit (STJE0010044)

SKU:
STJE0010044

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.136ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This IQGAP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Iqgap1
Gene ID: 29875
Uniprot ID: IQGA1_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in the kidney (at protein level).
Post Translational Modifications
Function Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest.
Protein Name Ras Gtpase-Activating-Like Protein Iqgap1
Database Links Reactome: R-MMU-373753
Reactome: -MMU-5626467
Reactome: -MMU-5674135
Reactome: -MMU-6798695
Reactome: -MMU-8980692
Reactome: -MMU-9013106
Reactome: -MMU-9013149
Reactome: -MMU-9013404
Reactome: -MMU-9013406
Reactome: -MMU-9013420
Reactome: -MMU-9013424
Cellular Localisation Cell Membrane
Nucleus
Cytoplasm
Apical Cell Membrane
Basolateral Cell Membrane
Subcellular Distribution Is Regulated By The Cell Cycle
Nuclear Levels Increase At G1/S Phase
Alternative ELISA Names Ras Gtpase-Activating-Like Protein Iqgap1 ELISA kit
Iqgap1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance