Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 28.5pg/mL |
Detection Limit: | 62.5-4000pg/mL |
Short Description: | This IL5Ra Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Il5ra |
Gene ID: | 16192 |
Uniprot ID: | IL5RA_MOUSE |
Sample Type: | serum, plasma or other biological fluids. |
Tissue Specificity | Expressed on eosinophils and basophils. Also on B-cells. |
Post Translational Modifications | |
Function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway. |
Protein Name | Interleukin-5 Receptor Subunit Alpha Il-5 Receptor Subunit Alpha Il-5r Subunit Alpha Il-5r-Alpha Il-5ra Cd Antigen Cd125 |
Database Links | Reactome: R-MMU-512988 Reactome: -MMU-5673001 Reactome: -MMU-912526 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative ELISA Names | Interleukin-5 Receptor Subunit Alpha ELISA kit Il-5 Receptor Subunit Alpha ELISA kit Il-5r Subunit Alpha ELISA kit Il-5r-Alpha ELISA kit Il-5ra ELISA kit Cd Antigen Cd125 ELISA kit Il5ra ELISA kit Il5r ELISA kit |
output |
Information sourced from Uniprot.org