| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse IL-23R-C-Fc protein was developed from hek293 cells and has a target region of C-Fc. For use in research applications. |
| Formulation: |
Lyophilized from a 0.2 Mu M filtered solution of PBS, pH 7.4 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Il23r |
| Gene ID: |
209590 |
| Uniprot ID: |
IL23R_MOUSE |
| Immunogen Region: |
Gly24-Asp372 |
| Immunogen: |
Recombinant Mouse IL-23R/IL-23 Receptor Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Gly24-Asp372) of mouse IL-23R/IL-23 Receptor (Accession #Q8K4B4) fused with an Fc tag at the C-terminus. |
| Post Translational Modifications | Phosphorylated in response to IL23. |
| Function | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
| Protein Name | Interleukin-23 ReceptorIl-23 ReceptorIl-23r |
| Database Links | Reactome: R-MMU-9020933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-23 Receptor proteinIl-23 Receptor proteinIl-23r proteinIl23r protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
